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Todd Phillips , the film's director, appears as Mr. Creepy, who appears briefly in an elevator. Professional skateboarder Mike Vallely portrays Neeco, the high-speed tuxedo delivery man.

The plot of The Hangover was inspired by a real event that happened to Tripp Vinson , a producer and friend of executive producer Chris Bender.

Vinson had gone missing from his own Las Vegas bachelor party, blacking out and waking up "in a strip club being threatened with a very, very large bill I was supposed to pay".

The story was about three friends who lose the groom at his Las Vegas bachelor party and then must retrace their steps to figure out what happened.

However, Lucas and Moore retained writing credit in accordance with the Writers Guild of America, West 's screenwriting credit system.

Ed Helms, Zach Galifianakis, and Bradley Cooper were all casual acquaintances before The Hangover was filmed, which Helms said he believed helped in establishing a rapport and chemistry amongst their characters.

Helms credited Phillips for "bringing together three guys who are really different, but really appreciate each others' humor and sensibilities".

We went through the wringer together, and that shared experience really made us genuine buddies. Lindsay Lohan was offered the role of Jade in the film.

However, she turned it down, saying that the script "had no potential". The Hangover was mostly filmed on location at Caesars Palace, including the front desk, lobby, entrance drive, pools, corridors, elevators, and roof, but the suite damaged in the film was built on a soundstage.

Helms said filming The Hangover was more physically demanding than any other role he had done, and that he lost eight pounds while making the film.

He said the most difficult day of shooting was the scene when Mr. Chow rams his car and attacks the main characters, which Helms said required many takes and was very painful, such as when a few of the punches and kicks accidentally landed and when his knees and shins were hurt while being pulled out of a window.

Jeong stated that his jumping on Cooper's neck naked wasn't a part of the script, but rather improvisation on their part.

It was added with Phillips' blessing. Jeong also stated that he had to receive his wife's permission to appear nude in the film.

Phillips tried to convince the actors to allow him to use a real Taser until Warner Bros. Regarding the explicit shots in the final photo slide show in which his character is seen receiving fellatio in an elevator, Galifianakis confirmed that a prosthesis was used for the scene, and that he had been more embarrassed than anyone else during the creation of the shot.

I really didn't even want it in there. I offered Todd's assistant a lot of money to convince him to take it out of the movie.

I did. But it made it in there. The scenes involving animals were filmed mostly with trained animals.

Trainers and safety equipment were digitally removed from the final version. Some prop animals were used, such as when the tiger was hidden under a sheet and being moved on a baggage cart.

Such efforts were given an "Outstanding" rating by the American Humane Association for the monitoring and treatment of the animals.

The film's score was composed by Christophe Beck. Pro-skater and punk musician Mike Vallely was invited with his band, Revolution Mother, to write a song for the film and also makes a cameo appearance as the high speed tuxedo delivery guy.

The Hangover was a financial success. It was tenth-highest-grossing film of in the world , the ninth-highest-grossing film of in the U.

On its first day of release in the U. There is a single-disc theatrical version featuring both fullscreen and widescreen options DVD only , as well as a widescreen two-disc unrated version of the film, also containing the theatrical version DVD, Blu-ray, and UMD.

The unrated version is approximately seven minutes longer than the theatrical version. The site's critical consensus reads, "With a clever script and hilarious interplay among the cast, The Hangover nails just the right tone of raunchy humor, and the non-stop laughs overshadow any flaw.

Roger Ebert of the Chicago Sun-Times gave it three-and-a-half stars out of four and praised the film for its funniness and comedic approach.

Scott later went on to say that the film is "safe as milk". LaSalle also praised the film's comedic scenes and called it "the funniest movie so far this year []".

Sharkey also said that the film is "filled with moments as softhearted as they are crude, as forgiving as unforgivable".

Conversely, Richard Corliss of Time said that "virtually every joke [in the film] either is visible long before it arrives or extends way past its expiration date" and added, "Whatever the other critics say, this is a bromance so primitive it's practically Bro-Magnon.

That may not seem like a big deal—a lot of funny movies play by their own rules—except that The Hangover keeps doubling-down on the outlandishness.

Anton Trees criticised the film for what he viewed as the weak character development, especially in its female characters.

The film's premise has several similarities to Dude, Where's My Car? The Las Vegas branch of Madame Tussauds added Hangover -themed rooms recreating the hotel room and the wedding chapel [57] and a tie-in rooftop cocktail bar.

In , Hasbro issued a parody version of their board game Clue where players have to locate a missing friend somewhere in the city after a wild night of carousing.

The film was released on May 26, From Wikipedia, the free encyclopedia. This article is about the film.

For other uses, see Hangover disambiguation. Theatrical release poster. Todd Phillips Daniel Goldberg. Jon Lucas Scott Moore. Chow, a flamboyant Chinese gangster Rachael Harris as Melissa, Stu's domineering, philandering girlfriend Mike Tyson as Himself Tyson originally refused to appear in the film, but he changed his mind when he found out that Todd Phillips directed Old School , which Tyson liked.

That's not the case in this movie. So as an actor, you can really play the intensity and gravity and seriousness of the moment, and just rely on the circumstances being funny.

The joke is kind of the situation you're in, or the way you're reacting to something, as opposed to the characters just saying something witty.

British Board of Film Classification. June 12, Retrieved November 22, The Numbers. Nash Information Services. Retrieved June 10, Box Office Mojo.

Internet Movie Database. Retrieved May 28, Retrieved August 8, The Huffington Post. Retrieved January 23, Retrieved November 23, Tyson added that the pic "started me on a good path to a healthy life.

December 6, June 19, Las Vegas Sun. The A. Retrieved June 11, The other cool thing is that the story of the movie is three guys kind of gradually becoming a lot closer and bonding, and that narrative actually informed our friendship—or the other way around.

As you spend 14 hours a day together for three months, you see a lot of sides of somebody. And I think you see that onscreen somewhat.

Deadline Hollywood. Retrieved June 8, Retrieved October 28, New York Post. June 29, Archived from the original on July 1, Retrieved July 12, Us Magazine.

July 8, Archived from the original on January 12, Instead, Lindsay Lohan, 23, declined the role of stripper Jade in The Hangover after declaring the screenplay "had no potential," Us Weekly reports in its latest issue on newsstands now.

Las Vegas Review-Journal. Retrieved May 18, Retrieved July 6, Not My Job: Ed Helms. Wait Wait Don't Tell Me! Radio broadcast. Retrieved June 9, Philippine Daily Inquirer.

The New York Times. Phillips does not always get his way. For a scene in which a police officer tests his stun gun on the guys, the director wanted his actors to be shot with a live Taser.

While the causes of a hangover are still poorly understood, [2] several factors are known to be involved including acetaldehyde accumulation, changes in the immune system and glucose metabolism, dehydration , metabolic acidosis , disturbed prostaglandin synthesis, increased cardiac output , vasodilation , sleep deprivation and malnutrition.

Beverage-specific effects of additives or by-products such as congeners in alcoholic beverages also play an important role.

Though many possible remedies and folk cures have been suggested, there is no compelling evidence to suggest that any are effective for preventing or treating alcohol hangover.

A hangover may also impair performance during potentially dangerous daily activities such as driving a car or operating heavy machinery.

An alcohol hangover is associated with a variety of symptoms that may include drowsiness, headache, concentration problems, dry mouth, dizziness, gastrointestinal complaints, fatigue, sweating, nausea , hyper-excitability, anxiety , and a feeling of general discomfort that may last more than 24 hours.

Some symptoms such as changes in sleep pattern and gastrointestinal distress are attributed to direct effects of the alcohol intoxication, or withdrawal symptoms.

The processes which lead to hangovers are still poorly understood. Additional associated phenomena are dehydration , metabolic acidosis , disturbed prostaglandin synthesis, increased cardiac output , vasodilation , sleep deprivation and insufficient eating.

After being ingested, the ethanol in alcoholic beverages is first converted to acetaldehyde by the enzyme alcohol dehydrogenase and then to acetic acid by oxidation and egestion process.

Consequences of the alcohol induced redox changes in the human body include increased triglyceride production, increased amino acid catabolism , inhibition of the citric acid cycle , lactic acidosis , ketoacidosis , hyperuricemia , disturbance in cortisol and androgen metabolism and increased fibrogenesis.

The metabolism of glucose and insulin are also influenced. Alcohol also induces the CYP2E1 enzyme, which metabolizes ethanol and other substances into more reactive toxins.

In particular, in binge drinking the enzyme is activated and plays a role in creating a harmful condition known as oxidative stress which can lead to cell death.

Acetaldehyde, the first by-product of ethanol, is between 10 and 30 times more toxic than alcohol itself [11] and can remain at an elevated plateau for many hours after initial ethanol consumption.

For example, some people predominantly East Asians have a mutation in their alcohol dehydrogenase gene that makes this enzyme unusually fast at converting ethanol to acetaldehyde.

In addition, about half of all East Asians convert acetaldehyde to acetic acid more slowly via acetaldehyde dehydrogenase , causing a higher buildup of acetaldehyde than normally seen in other groups.

Since the alcohol flush reaction is highly uncomfortable and the possibility of hangovers is immediate and severe, people with this gene variant are less likely to become alcoholics.

Acetaldehyde may also influence glutathione peroxidase , a key antioxidant enzyme, and increases the susceptibility to oxidative stress.

One study found that injecting sodium acetate into rats caused them to have nociceptive behavior headaches. In addition, there is a biochemical explanation for this finding.

High acetate levels cause adenosine to accumulate in many parts of the brain. But when the rats were given caffeine, which blocks the action of adenosine, they no longer experienced headaches.

In addition to ethanol and water, most alcoholic drinks also contain congeners , either as flavoring or as a by-product of fermentation and the wine aging process.

While ethanol is by itself sufficient to produce most hangover effects, congeners may potentially aggravate hangover and other residual effects to some extent.

Congeners include substances such as amines , amides , acetones , acetaldehydes, polyphenols , methanol, histamines , fusel oil , esters , furfural , and tannins , many but not all of which are toxic.

In general, dark liquors have a higher concentration while clear liquors have a lower concentration.

Whereas vodka has virtually no more congeners than pure ethanol, bourbon has a total congener content 37 times higher than that found in vodka.

Several studies have examined whether certain types of alcohol cause worse hangovers. One even showed that hangovers were worse and more frequent with darker liquors.

One potent congener is methanol. It is naturally formed in small quantities during fermentation and it can be accidentally concentrated by improper distillation techniques.

Metabolism of methanol produces some extremely toxic compounds, such as formaldehyde and formic acid , which may play a role in the severity of hangover.

Ethanol slows the conversion of methanol into its toxic metabolites so that most of the methanol can be excreted harmlessly in the breath and urine without forming its toxic metabolites.

This may explain the temporary postponement of symptoms reported in the common remedy of drinking more alcohol to relieve hangover symptoms.

This delayed action makes it an attractive candidate explanation for delayed post-intoxication symptoms and correlations between methanol concentrations and the presence of hangover symptoms that have been found in studies.

The metabolic processes required for alcohol elimination deplete essential vitamins [26] and electrolytes. After a night of drinking, the resulting lack of key B and C vitamins, as well as potassium, magnesium, and zinc may cause fatigue, aching and other hangover-like symptoms.

Ethanol has a dehydrating effect by causing increased urine production diuresis , which could cause thirst, dry mouth, dizziness and may lead to an electrolyte imbalance.

Studies suggest that electrolyte changes play only a minor role in the genesis of the alcohol hangover and are caused by dehydration effects.

Drinking water may help relieve symptoms as a result of dehydration but it is unlikely that rehydration significantly reduces the presence and severity of alcohol hangover.

In current research, the significant relationship between immune factors and hangover severity is the most convincing among all factors so far studied.

Especially the hangover symptoms nausea, headache, and fatigue have been suggested to be mediated by changes in the immune system.

The concentration of several cytokines have been found to be significantly increased in the blood after alcohol consumption.

These studies suggest that the presence and severity of hangover symptoms can probably be reduced by administration of a cyclooxygenase inhibitor such as aspirin or ibuprofen.

Several factors which do not in themselves cause alcohol hangover are known to influence its severity.

These factors include personality, genetics, health status, age, sex, associated activities during drinking such as smoking, the use of other drugs, physical activity such as dancing, as well as sleep quality and duration.

Hangovers are poorly understood from a medical point of view. Within the limited amount of serious study on the subject, there is debate about whether a hangover may be prevented or at least mitigated.

There is also a vast body of folk medicine and simple quackery. A four-page literature review in the British Medical Journal concludes: "No compelling evidence exists to suggest that any conventional or complementary intervention is effective for [35] preventing or treating alcohol hangover.

The most effective way to avoid the symptoms of alcohol induced hangover is to avoid drinking. Some compounds reduce specific symptoms such as vomiting and headache, but are not effective in reducing other common hangover symptoms such as drowsiness and fatigue.

Some sources indicate there is no evidence that any treatments for hangovers are effective. Recommendations for foods, drinks and activities to relieve hangover symptoms abound.

The ancient Romans , on the authority of Pliny the Elder , favored raw owl 's eggs or fried canary , [39] while the " prairie oyster " restorative, introduced at the Paris World Exposition, calls for raw egg yolk mixed with Worcestershire sauce , Tabasco sauce , salt and pepper.

Alcoholic writer Ernest Hemingway relied on tomato juice and beer. A somewhat dated French idiomatic expression for hangover is "mal aux cheveux", literally "sore hair" or "[even] my hair hurts".

Alcohol hangover has considerable economic consequences. A British study found that alcohol use accounted for 3. In Canada 1. In Finland , a country with a population of 5 million persons, over 1 million workdays are lost each year because of hangovers.

The average annual opportunity cost due to hangovers are estimated as USD per working adult. Potentially dangerous daily activities such as driving a car or operating heavy machinery are also negatively influenced.

In mid, it was reported that one company in the UK allows sick days when hung over. Psychological research of alcohol hangover is growing rapidly.

From Wikipedia, the free encyclopedia. For the film, see The Hangover. For other uses, see Hangover disambiguation.

Hangover Deutsch Video

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Taio Cruz - Hangover ft. Flo Rida (Auf Deutsch!)

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